Resolution Solution September 2008

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Want to learn more about our Process media products? Here’s your chance. This issue of Resolution Solution features information on our NEW Toyopearl GigaCap ion exchange resins, spotlighting their high capacities and fast elution kinetics. Speaking of ion exchange resins, we just introduced new non-porous, large particle size ion exchange columns that enable fast equilibration and analysis of complex biomolecular samples. Read more below for the details on these TSKgel STAT columns and about much more that Tosoh Bioscience has to offer!

Regards,

Cara Tomasek
Group Marketing Manager, Laboratory Products

And now a word from our customers...

LCGC: A Hydrophilic Interaction Chromatography Method for the Purity Analysis of Cytosine
LCGC, Vol 26, No 7: pp 632-642 (July 2008)
Mark Strege, Charles Durant, John Boettinger, and Michael Fogarty

A HILIC method (Hydrophilic Interaction Chromatography) was developed using a TSKgel Amide-80 column for the determination of cytosine purity. The HPLC system was equipped with electrospray ionization mass spectrometry detection for confirmation of the identity of selected related impurities.

New from the Leaders in Bioseparation...

Available now! The TSKgel STAT columns feature high performance IEC separations when you need answers fast. TSKgel STAT columns are applicable to a broad range of applications in research and quality control, such as:

v the monitoring of PEGylation reactions,

v the analysis of plasmids or DNA fragments.

v the separation of monoclonal antibody variants & aggregates, drug candidates and siRNA

Want to know more? Look for the TSKgel STAT columns on these pages:

TSKgel Anion Exchange Columns
TSKgel Cation Exchange Columns

BioProcess International: Reducing Elution Volumes with High Capacity and Improved Mass Transfer Ion Exchange Resins
BioProcess International, Vol. 6, No. 7: pp 108-110 (July 2008)
Al Jackewitz

This article spotlights the new Toyopearl GigaCap ion exchange resins and shows breakthrough curve data demonstrating their high capacities and fast elution kinetics being applied to reducing elution pool volumes

Brochure

BR04: Toyopearl GigaCap Ion Exchange Resins

Includes the dynamic binding capacities, breakthrough curve kinetics, and other physical properties of three new fast mass transfer ion exchange resins, along with competitive comparisons. Selectivities of the two new cation exchange resins are also compared.

Toyopearl GigaCap S-650M (strong cation)
Toyopearl GigaCap CM-650M (weak cation)
Toyopearl GigaCap Q-650M (strong anion)

Product Overviews

PO21: Toyopearl GigaCap CM-650M

Toyopearl GigaCap CM-650M is the second cation exchange resin in the Toyopearl GigaCap family, optimized for high throughput purification of IgG. Its base bead is Toyopearl HW-65C which has a particle size range of 50-100μm. This particle size range has outstanding pressure flow characteristics for high throughput IgG purification

PO22: TSKgel SP-STAT and TSKgel CM-STAT columns

TSKgel SP-STAT and TSKgel CM-STAT cation exchange columns allow fast equilibration and analysis, as well as isolation, of complex biomolecules. These columns offer very efficient chromatography for high as well as low MW solutes - made possible by novel bonding chemistry and the absence of micro-pores.

Streamlined Website

The HPLC columns channel of our website has been redesigned to improve navigation. With a columns overview page, now there are fewer clickthroughs required to get to a specific product page. See for yourself...

6th HIC-RPC Bioseparation Conference
March 15-19, 2009

Second call for abstracts – submission deadline is Oct. 31st. Online registration will be available soon. Get all the details on this conference for the advancements, applications and theory of HIC and RPC in downstream processing.

Upcoming Events
Join us to see all that's new!

October 16-18, 2008
• NIH Research Festival Exhibit
Bethesda, MD

November 17-20, 2008
• Eastern Analytical Symposium
Somerset, NJ

Promotions

Create some magic in your lab today!

Buy one analytical reversed phase column and receive a second reversed phase column item* of equal or lesser value at no charge!

Plus the first 150 orders receive a genie-ous t-shirt!

Educational and governmental institutions save 15% on all HPLC columns and laboratory size resin containers (< 1L).

For the details on these promotions, please see our promo page.

Introducing…
Ms. Reba Holley, the newest member of our sales team.

Interested In a Career with Tosoh Bioscience?

Check out our current openings to join a dynamic, growing company!

PO23: TSKgel Q-STAT and TSKgel DNA-STAT columns

TSKgel Q-STAT and TSKgel DNA-STAT anion exchange columns are packed with monodisperse, non-porous resin particles of which the surface consists of an open access network of multi-layered anion exchange groups. The TSKgel Q-STAT columns are packed with 7 or 10μm particles, the TSKgel DNA-STAT column with 5μm particles.

Ask the Experts
(Feel free to email us your question and be sure to check out our extensive FAQ pages.)

Question: What is the cause of negative peaks? Answer

Question: What is GPC? Answer

Question: What is the difference between a monomeric and polymeric C18 bonded phase? Answer

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