Our applications lab has been busy!  Browse the following list of technical information sheets for our latest applications.

• Analysis of Methyl Methacrylate Monomer in Acrylic Denture Base Resin (TIS115)
  Following the residual monomer analysis specified in the Japanese Industrial Standards (JIS) T6501 for GPC and HPLC, residual methacrylate monomers were measured.
• Analysis of Aminoglycoside Antibiotics by LC-MS (TIS116)
  HPLC is used to measure concentrations of glycoside antibiotics containing amino sugars in blood and foods by reverse phase chromatography using an ion-pair reagent.
• Analysis of Microcystins by LC/MS (TIS117)
  The levels of microcystins LR, RR and YR were measured by LC/MS as a drinking water test method.
• Simultaneous Analysis of Sulfa Drugs (TIS118)
  Different sulfa drugs were simultaneously analyzed using formic acid and methanol as a mobile phase.
• High-Sensitivity Concurrent Determination of Omeprazole and its Two Metabolites in Human Plasma by Column-Switching High Performance Liquid Chromatography (TIS119)
  The plasma levels of omeprazole, a proton pump inhibitor (PPI), and its metabolites were concurrently determined using TSKgel ODS-100Z 5µm.
• Concurrent Analysis of Sulfa Drugs by LC/MS (TIS120)
  Sixteen sulfa drugs and trimethoprim, a synthetic antibacterial agent often coadministered with sulfa drugs, were measured using an MS detector.
• Simultaneous Analytical Method I for Agricultural Chemicals using LC/MS (Agricultural Products) (TIS121)
  Forty two components in agricultural chemicals underwent simultaneous analyses using TSKgel ODS-100V 3μm.
• Analysis of Malachite Green and Leucomalachite Green by LC/MS (TIS122)
  Malachite Green and its metabolite Leucomalachite were simultaneously analyzed using a solvent with an acid composition, according to LC/MS procedures as regulated by the Ministry of Health, Labour, and Welfare.
• Analysis of 2AB-labeled Isomaltooligosaccharides by LC/MS (TIS123)
  By optimizing conditions using the TSKgel Amide-80 3 µm as the separating column, good separation/identification of a sugar chain derivatized with 2-aminobenzoic acid was achieved.
• HPLC Analysis of OTC Antipyretic Analgesics (TIS124)
  Comparative analyses of OTC antipyretic analgesics were conducted by reverse-phase HPLC using the TSKgel ODS-100V 5µm.
• Analysis of Chloramphenicol in Honey by LC/MS (TIS125)
  Analysis of an added sample of the microbial chloramphenicol in honey was conducted by LC/MS.
• Analysis of Fungicides in Disposable chopsticks by HPLC (TIS126)
  Disposable chopsticks were tested for four fungicides: imazalil (IMZ), which was analyzed individually, and orthophenylphenol (OPP), thiabendazole (TBZ), and diphenyl (DP), which were analyzed simultaneously.
• Simultaneous Analysis of Veterinary Drugs by LC-MS/MS (1) (TIS128)
  A standard sample of drugs on the Positive List, including 21 components in veterinary drug mixture PL-1-3, were separated using LC-MS/MS.
• Simultaneous Analysis of Veterinary Drugs by LC-MS/MS (2) (TIS129)
  A standard sample of drugs on the Positive List, including 24 components in veterinary drug mixture PL-2-1, were separated using LC-MS/MS.
• Analysis of Free Trans Fatty Acids in Oil and Fat by HPLC (TIS130)
  Trans fatty acids, targeting major trans fatty acid elaidic acis (9t-18:1, trans isomer of oleic acid), were analyzed by HPLC after fluorescent derivatization using an ADAM reagent.
• Analysis of Synthetic Sweeteners in Coffee by HPLC (TIS131)
  Acesulfame-K, a synthetic sweetener, and saccharine were simultaneously analyzed in coffee using a hydrophilic interaction liquid chromatography (HILIC) column.
• Analysis of Methamidophos and Acephate in Tea by LC-MS/MS (TIS132)
  Methamidophos and acephate were simultaneously analyzed using a simulated sample created by adding standard substances to tea.
• Analysis of Methotrexate and its Polyglutamate Metabolites in Plasma by LC-MS/MS (TIS135)
  Anticancer drug MTX and its metabolite 7-OH-MTX were analyzed using reverse-phase chromatography, while MTX and its polyglutamate metabolites were simultaneously analyzed in a plasma sample using hydrophilic interaction liquid chromatography (HILIC).
• Separation of Simvastatin by HPLC (TIS136)
  A standard sample of simvastatin, used as a drug to treat hyperlipidemia, was separated using HPLC.
• Measurement of Molecular Mass of Lignin by GPC with Aqueous Solution (TIS137)
  The molecular mass of lignin was measured by SEC using a DMSO/DMF mixed solvent with an added acid.
• Analysis of Chromium (III) Picolinate in Supplements by HPLC (TIS138)
  Chromium picolinate was analyzed by HPLC in diet supplements.
• Analysis of Cyclodextrins in Instant Food: Application Example using an Evaporative Light Scattering Detector (ELSD) (TIS139)
  Three types of cyclodextrins used in Japan were separated using the HILIC mode and detected by ELSD.
• Analysis of Sweetener (Sucralose) in Coffee: Application Example Using an Evaporative Light Scattering Detector (ELSD) (TIS140)
  Sucralose in a coffee beverage (sugarless) was analyzed using ELSD detectors in combination with an HILIC column, while synthetic sweeteners aspartame and glycyrrhizic acid were simultaneously analyzed.
• Analysis of Sweeteners (sugar alcohols) in Food: Application Example Using Evaporative Light Scattering Detector (ELSD) (TIS141)
  Various sugar alcohols were separated using the HILIC in gradient elution and detected by ELSD, while sugar alcohols in sugarless candy and functional jelly beverages were analyzed.
• Gradient Separation of Oligosaccharides in Alcoholic Beverages (TIS142)
  Following the separation of oligosaccharides by HILIC mode, evaporative light scattering was used to detect the sample components.
• Separation of Vitamin A Isomers (TIS143)
  All-trans and 9-cis retinol isomers were analyzed using a TSKgel C18 column
• Separation of Triglycerides in Cooking Oil (TIS144)
  Non-aqueous reversed phase application showing the analysis of triglycerides using a gradient of tetrahydrofuran in acetonitrile and evaporative light scattering detection
• Analysis of Inositol in Health Drinks (TIS145)
  TSKgel Amide-80 HILIC analysis of inositol under gradient elution conditions
• Analysis of Related Substances in Cefcapene Pivoxil Hydrochloride by SEC (TIS146)
  Analysis of impurities in cefcapene pivoxil hydrochloride, a cephem antibiotic, using a size exclusion column with an organic solvent
• Molecular Mass Determination of Polyacrylonitrile by SEC (TIS147)
  Fast and reproducible analysis of polyacrylonitrile within 12 minutes with within-day reproducibility of 0.6-1.4% and between-day reproducibility over 3 days of 1%.
  
• Analysis of Kasugamycin and Validamycin in Tea Leaf by LC-MS (TIS148)
  A HILIC method for these highly polar substances was used since retention is difficult in the reversed phase mode using a C18 column.
  
• Analysis of Dicyandiamide in Chemical Fertilizer (TIS149)
  TSKgel NH2-100 HILIC analysis
  
• Analysis of Imidazole Dipeptides in Meat (TIS150)
  An amino column in the HILIC mode was used as an alternative to a reversed phase column with an ion pair reagent or ion exchange.
  
• Analysis of 5-Fluorouracil in Plasma by LC-MS/MS (TIS151)
  An application of 5-FU in a plasma sample using a TSKgel Amide-80 column with recovery of > 87% was obtained
  
• Analysis of Oseltamivir Carboxylate in River Water by LC-MS/MS (TIS152)
  An LC-MS/MS method, based on a TSKgel ODS-100V, 3µm reversed phase column using OC obtained by alkaline hydrolysis of OP
  
  

In addition....you can search thousands of applications by compound, separation mode, column, or detector in the extensive HPLC application database maintained by Tosoh Corporation (the parent to Tosoh Bioscience LLC). 

Please click here to browse the database.

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