The silica-based TSK-GEL reversed phase product line consists of eleven stationary phases designed for the analysis of low molecular weight analytes such as:
- pharmaceutical drugs
- forensic compounds
- derivatized amino acids
- carbohydrates
- steroids, lipids, fatty acids
Depending on their molecular weight, peptides may be analyzed with the same silica-based RPC columns, while proteins require a larger pore size column (200-300 angstrom ).
TSK-GEL silica packings are spherical with uniform pore sizes of 100, 140, 150, or 250 angstrom bonded with a monomeric or polymeric layer of octadecyl, octyl, cyano, trimethylsilyl or phenyl groups. Several of the stationary phases are subsequently capped with trimethylsilyl groups by a proprietary method that deactivates the unreacted but accessible silanol groups.
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100Å Monomeric
RP Silica |
80Å Monomeric
RP Silica |
2µm Super Series
RP Silica |
Specialty
RP Silica |
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This latest generation of highly pure 100Å pore size silica is the foundation for sophisticated bonding chemistries.
These are the preferred columns for demanding separations of polar (ODS-100V) and small MW basic compounds (ODS-100Z).
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The 100Å pore size makes this column type ideal for samples smaller than 6,000 Da molecular weight. This product line features exhaustively endcapped 80Ts columns for basic solutes and the moderately endcapped 80Tm columns for peptide separations.
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The “Super Series” provides higher efficiency and improved resolution over conventional columns packed with 3 and 5μm particles.
Pore size of 140Å makes the “Super Series” columns most suitable for samples with molecular weight below 10,000 Da molecular weight.
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TSK-GEL specialty RP silica columns were developed to provide optimum separation for:
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