TSK-GEL Alpha and SuperAW columns were developed for the GPC analysis of polymers of intermediate polarity. As in the PW- and PWxl-type resins, the particles in TSK-GEL Alpha and SuperAW columns have a hydroxylated methacrylate polymer backbone, but they are crosslinked to a higher degree than PW- and PWxl-type columns to minimize swelling in polar organic solvents. TSK-GEL Alpha and SuperAW particles are available in a wide variety of pore sizes. - Use semi-micro TSK-GEL SuperAW columns for high-throughput applications to reduce solvent consumption to reduce solvent disposal cost. - Use TSK-GEL Alpha columns when analysis time is not critical when sample mass is not limited to collect fractions to obtain maximum number of plates (at the expense of analyis time).

Highlights: Alpha and SuperAW columns Particle sizes SuperAW, 4-9μm particles Alpha, 7-13μm particles No or minimal swelling in a wide range of polar organic solvents: methanol, acetonitrile, DMSO, isopropanol, THF, and HFIP. For high thoughput applications, TSK-GEL SuperAW columns provide equivalent resolution in 1/2 the time compared to TSK-GEL Alpha columns. Accurate MW determination and normal retention of polystrene polymers in DMF solvent. System peaks from salts in the eluent elute away from the oligomer of interest. Applications: polymers that are soluble in methanol, acetonitrile, DMSO, isopropanol, or THF; can also be used for water-soluble polymers.

TSK-GEL SuperAW	TSK-GEL Alpha
TSK-GEL SuperAW column line consists of five columns and a mixed-bed column. High efficiency TSK-GEL SuperAW columns are only available in 6.0mm ID x 15cm columns for High Throughput applications. TSK-GEL Alpha column line consist of five columns and a mixed-bed column. TSK-GEL Alpha columns are available in conventional 7.8mm ID x 30cm column formats.

Return to Size Exclusion main

Application Overview -- Gel Filtration Chromatography with TSK-GEL columns