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Tosoh Bioscience LLC: The Chemistry of Innovation
Ion Exchange Chromatography
HPLC Columns
Anion Exchange
Cation Exchange
TSKgel BioAssist S
TSKgel CM-2SW
TSKgel CM-3SW
TSKgel CM-5PW
TSKgel CM-STAT
TSKgel OApak-A
TSKgel SCX
TSKgel SP-2SW
TSKgel SP-5PW
TSKgel SP-NPR
TSKgel SP-STAT


TSK-GEL CM-STAT columns are packed with 7 and 10µm hydrophilic non-porous resin particles of which the surface consists of an open access network of multi-layered weak cation exchange groups. The innovative bonding chemistry, combined with a relatively large particle size, results in a respectable loading capacity, low operating pressure and rapid analysis.

Applications for the TSK-GEL CM-STAT columns include the separation of proteins, protein aggregates, charge isomers of monoclonal antibodies, PEGylated proteins, and peptide digests.

 

Product Attributes:

 Matrix:   hydrophilic polymer
 Particle size (mean): 7µm and 10µm
 Pore size (mean): non-porous
 Functional group: carboxymethyl
 Counter ion: Na
 pH range: 3.0 - 10.0
 Static binding 
 capacity (mg 
 Lysozyme/mg dry gel):
ca. 20 (7µm)
ca. 15 (10µm)
 Small ion capacity: 100ueq/g dry gel
 pKa: 4.9



Literature:

Technical Presentation -- High Speed and High Resolution Cation Exchange Chromatography for Biological Samples on Non-Porous Packings 

Operating Conditions and Specifications

Product Overview -- TSK-GEL CM-STAT Cation Exchange Columns

Brochure -- TSK-GEL HPLC Columns for Biomolecular Applications

 

 Applications


 The analysis profiles for five antibodies on a TSKgel CM-STAT column were compared with the profiles obtained on a competitive non-porous cation exchange column. Similar or higher resolution profiles were obtained on the TSKgel CM-STAT column in approximately half the time.


TSKgel CM-STAT, 4.6mm ID x 10cm

ProPac WCX-10, 4mm ID x 25cm

 

Ordering information:
To place an order please click on the shopping cart next to the desired item, or contact Customer Service. Tosoh Bioscience LLC only accepts orders from customers in North and South America. For sales offices in other parts of the world, please click Locations.

P/N
Description
Particle
size
Housing materialID
(mm)
Length
(cm)
Price ($)
21965
TSKgel CM-STAT
10µm
Stainless Steel33.5876Add to Cart
21966
TSKgel CM-STAT
7µm
Stainless Steel4.610927Add to Cart


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Frequently asked questions -- IEC

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Tosoh Bioscience LLC  156 Keystone Drive, Montgomeryville, PA, 18936  Tel: (215) 283-5000  Email: info.tbl@tosoh.com