TSKgel ODS-140HTP columns provide high resolution and short analyses time at moderate pressures, enabling high throughput separations.  The polylayer bonding chemistry of the 2µm* particle size of these columns results in highly efficient and durable columns.  The lower pressure drop reduces the burden on the hardware, allowing the TSKgel ODS-140HTP columns to be used with either UPLC^® (up to 9000psi) or conventional HPLC systems.

For use in high throughput applications, including drug discovery, pharmacokinetics and peptide digest separations, TSKgel ODS-140HTP columns offer excellent peak shape for basic compounds.

* nominal particle size; mean particle size is 2.3µm.

Structure:

Product Attributes:

Pore size (silica): 140Å  Endcapped: yes  Particle size: 2.3µm  pH stability: 2.0 - 7.5  Functional group:  C18 (polymeric bonding chemistry)  % carbon 8%

Literature:

Application Note -- High Throughput Reversed Phase HPLC Analysis of Caffeine using TSKgel ODS-140HTP and ODS-100V Columns

Application Note -- TSKgel ODS-140HTP, 2.3µm: Ultra High Performance Reversed Phase Columns for High Throughput Analysis

Application Note -- TSKgel ODS-140HTP, 2.3μm Columns for the Fast and Reliable Separation of Drugs Used in Cold and Sinus OTC Medicines

Catalog -- Reversed Phase Columns, silica-based

Operating Conditions and Specifications

Product Overview -- TSKgel ODS-140HTP Columns

Technical Presentation -- The Separation of Popular Cold, Sinus, and Allergy Medications using TSKgel ODS-140HTP Columns

Technical Presentation -- High Throughput Analysis of Caffeine and Other Food and Beverage Additives Present in Popular Soft Drinks using High Performance Reversed Phase HPLC

Technical Presentation -- High Throughput Analysis of a Number of Common Drugs using a TSKgel ODS-140HTP, 2.3μm Column (ACS 2009)

Technical Presentation -- High Throughput Analysis of a Number of Common Drugs using TSKgel ODS-140HTP Columns (EAS 2009)

Technical Presentation -- Analysis of a Number of Common Drugs using TSKgel ODS-140HTP, 2.3μm High Throughput Reversed Phase Columns (Pittcon 2010)

Technical Presentation -- High Throughput Separation of Hypertension Drug Standards by Reversed Phase Chromatography using TSKgel ODS-140HTP, 2.3µm Columns (ASMS 2010)

Technical Presentation -- High Throughput Analysis of Orlistat® Drug Standard and Corresponding Non-Prescription Over-The-Counter Drug alli® using TSKgel ODS-140HTP, 2.3μm Columns (HPLC 2010)

Technical Presentation -- Analysis of an Anti-Obesity OTC Drug alli® (orlistat) using a High Throughput Reversed Phase Column (ACS Fall 2010)