Toyopearl GigaCap Q-650 media is a high capacity anion exchange resin* optimized for the capture and purification of both small and large proteins. Toyopearl HW-65 resin is the polymeric base bead chemically modified to provide a higher number of anionic binding sites for increased resin capacity . It exhibits typical dynamic binding capacities in the vicinity of 175mg/mL for BSA (66kD) and 49mg/mL for thyroglobulin (660kD).
This new polymer product maintains high capacity at increased linear velocities, has good pressure flow characteristics and will withstand back pressures up to 3 bar. The new higher capacity and back pressure stability of Toyopearl GigaCap Q-650 resin creates opportunities for increased throughput in all anion exchange purification steps.
In addition to the high DBC and good pressure flow characteristics, Toyopearl GigaCap Q-650 media displays excellent binding and elution kinetics, which results in a more concentrated protein fraction collected during the elution step. (data)
*specifically designed for packed bed use
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