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Tosoh Bioscience LLC: The Chemistry of Innovation
What's New
September 2008
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This latest issue of our e-newsletter is full of detailed information to help familiarize you with the array of HPLC column solutions Tosoh Bioscience has to offer. You’ll find a great article that was recently published discussing the use of our popular HILIC product, TSKgel Amide-80, in a LC/MS technique. We have several new separation reports for your review, all of which detail SEC columns, and our tech service department has pitched in to address some frequently asked questions. Have you heard about our latest promotion designed to save your lab money? Check it out and enjoy this issue of Resolution Solution.

Regards,

Cara Tomasek
Marketing Manager, Laboratory Products

And now a word from our customers...

Journal of Chromatography A: Development of a comprehensive two-dimensional hydrophilic interaction chromatography/quadrupole time-of-flight mass spectrometry system and its application in separation and identification of saponins from Quillaja saponaria

Journal of Chromatography A, Volume 1181, Issues 1-2,
15 February 2008, Pages 51-59
Yuan Wang, Xin Lu, Guowang Xu

Hydrophilic interaction chromatography (HILIC) was used in two dimensions in a comprehensive two-dimensional HILIC hyphenated with a quadrupole time-of-flight mass spectrometry (HILIC × HILIC-Q-TOF-MS) system for the analysis of complex samples of hydrophilic compounds. A TSKgel Amide-80 column was employed as the first dimension…


Separation Reports

SR105: Semi-micro Columns for Size Exclusion Chromatography in Organic Solvent Systems: TSK-GEL SuperMultiporeHZ Series Columns

SEC is a method for calculating molecular weight from a calibration curve created using molecular weight standards. However, challenges arise when SEC is used to analyze polymers with a wide molar mass distribution, namely distortion of the chromatogram or deviations between the actual calibration curve and the calibration curve approximated from data obtained from the molecular weight standards. TSK-GEL SupermultiporeHZ Series SEC columns contain particles that are mono-disperse in size and exhibit a broad range of pore sizes. This multi-pore particle synthesis technology, developed by Tosoh scientists, ensures that each particle has an extended linear calibration curve, thereby greatly diminishing chromatograms with inflection points.

SR094: Analyzing Polymers that are More Soluble in Polar-Organic Solvents with TSK-GEL Alpha Series Columns

Size-exclusion columns are usually classified into the following types: columns for aqueous solvent systems and columns used with an organic solvent systems. However, multiple problems have occurred with each of these types of columns when used to study polar polymer molecules. With the use of TSK-GEL Alpha Series columns, a variety of solvents can be chosen ranging from aqueous solutions to organic solvents, making it possible to set the conditions for investigation based on the solubility of the chemical and the molecular weight standard. As a result, this series of columns can be used when analyzing polar polymer samples that have been so cumbersome to characterize with traditional SEC columns in the past.

SR028: Principles and Applications of High Performance GPC Columns: TSK-GEL Hxl Type Columns for Oligomer Analysis

In general, analysis by conventional GPC is more time consuming than separation by reversed phase or normal phase HPLC. The TSK-GEL Hxl type columns provide a significant improvement in this regard, by reducing analysis time over more conventional GPC column types. Using TSK-GEL Hxl type columns yields a number of major advantages, including reducing analysis time by half, increasing analysis performance, and decreased solvent consumption and disposal costs.

 

Upcoming Events
Join us to see all that's new!

August 17-21, 2008
Fall ACS National Meeting
and Expo
Philadelphia, PA

October 16-17, 2008
NIH Research Festival Exhibit
Bethesda, MD

November 17-20, 2008
Eastern Analytical Symposium
Somerset, NJ 


 

Promotions

 

Create some magic in your lab today!

 

Buy one analytical reversed phase column and receive a second reversed phase column item* of equal or lesser value at no charge!

Plus the first 150 orders receive a genie-ous t-shirt!


Class? Can you spell
S-A-V-I-N-G-S?

Educational and governmental institutions save 15% on all HPLC columns and laboratory size resin containers (< 1L).

For the details on these promotions, please click here.

 

Introducing…
Ms. Regina Huelgas, the newest member of our sales team.

 

Interested In a Career with Tosoh Bioscience?

Check out our current openings to join a dynamic, growing company!

Application Notes

AN17: TSK-GEL ODS-140HTP, 2.3µm: Ultra-High Performance Reversed Phase Columns for High Throughput Analysis

TSK-GEL ODS-140HTP, 2.3µm reversed phase HPLC columns provide high resolution and short analyses times at moderate pressures. For use in high throughput applications, including drug discovery, pharmacokinetics and peptide digest separations, these 2.3µm columns offer excellent resolution.

 

Ask the Experts
(Feel free to email us your question and be sure to check out our extensive FAQ pages.)

Question: How do mixed-bed columns differ from your “multipore” columns? Answer

Question: How do you assemble a guard column kit? Answer

 

Tosoh Bioscience LLC  156 Keystone Drive, Montgomeryville, PA, 18936  Tel: (215) 283-5000  Email: info.tbl@tosoh.com