Process Development


The MiniChrom TOYOPEARL CM-650S column is a small, pre-packed column (8 mm ID × 10 cm) with 5 mL resin volume designed for fast method development or resin screening. MiniChrom columns guarantee optimal performance and can be connected to common high or medium pressure liquid chromatography systems.

MiniChrom columns are packed by Atoll GmbH. They are reproducibly and individually flow-packed to account for the varying compressibility of each resin. Therefore, each column provides an accurate representation of resin performance that translates to full scale production columns.


P/NDescriptionResin VolumeParticle Size (µm)   Price
45182MiniChrom TOYOPEARL CM-650S5 mL35  220

Product Attributes

Base bead: HW-65
Pore size (mean): 100 nm
Particle size (mean): 35 µm
Ligand type: weak cation
Ligand pKa: 3.6
DBC: 30 - 50 g/L
Pressure rating: 0.3 MPa
Shipping buffer: 20% ethanol
pH stability: 2-13




Code #DescriptionLiterature Type
PCAT07 TOYOPEARL, TSKgel and Ca⁺⁺Pure-HA Bulk Resin 2019 Product Guide -- Process DevelopmentProduct Catalog
PO40 MiniChrom Columns for TOYOPEARL, TSKgel and Ca⁺⁺Pure-HA ResinsProduct Overview
RIS0020 TOYOPEARL CM-650Resin Information Sheet